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Transdermal nicotine patch is commonly the first choice because it yields higher compliance rates than other NRT products [8]

In light of its superior safety profile, Health Canada mandated a label change in 2013 advising thorough consideration of NRT before prescribing either varenicline or bupropion to any smoker, further stating that in many cases, nicotine replacement therapy should be tried before prescribing varenicline or bupropion [9], emphasizing the need to optimize the effectiveness of this first-line medication

and suicidal behaviours

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COPD is a permanent, incurable, and often fatal reduction in the capacity of the lungs, reducing the lungs ability to fully exhale air