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Future studies with larger and more diverse participant pools would help to capture the variability in individual responses better and provide more robust data

Possible interaction with HPA-axis hormones

Behav Brain Res 171(2):279285

The KOA cases presented with clinical signs of severe OA, KellgrenLawrence grade 34, and met the criteria set by the Finnish Ministry of Social Affairs and Health for arthroplasty

Metabolic alterations have often been found in cancer cells, as cancer cells have a higher demand for ATP and other metabolites to sustain their unlimited proliferation and growth, and the higher metabolic activity in cells would lead to more ROS generation due to more mitochondria respiration