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Population health benefits are found in scenarios where (1) the use of e-cigarettes increases only among smokers who are interested in quitting, (2) there is no increased initiation of e-cigarette use among nonsmokers, and (3) e-cigarettes are used only by youth who would otherwise have smoked conventional cigarettes

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SWIC is meant to appeal to tobacco users who want to inhale a stronger tobacco flavor than vaping liquids now deliver, but that does not look like a cigarette, which Altria thinks will appeal to smokers who might feel embarrassed when others see them smoking, or who worry others will be offended by that stale smell of smoke

Thus, zebrafish embryos are considered a New Alternative Model (NAM)