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The use of cyclodextrins in pharmaceutical formulations or compositions is well known in the art as cyclodextrins and cyclodextrin derivatives are often used to improve the solubility of a drug

Most research on the peptide has been conducted in animal models rather than human clinical trials

Another method involves the use of selenium-enriched yeast containing selenomethionine, a methionine analog where selenium replaces sulfur, which serves as a marker for digestible methionine

PubMed Cashin-Hemphill L, Spencer CA, Nicoloff JT, et al