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1 Participants had their heart rates and systolic and diastolic blood pressures monitored prior to drug administration and approximately 30 minutes after drug administrationwhen nicotine reaches its peak plasma nicotine level

Cigarette smoke extract: A preclinical model of tobacco dependence

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The purpose of the advertisements were ultimately to get the women to consume a product such as tobacco, and to use messages to convince the consumer that it was a need rather than merely desire