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Nat Rev Endocrinol (2014) 10:13642

The cell-specific toxic outcome of the ubiquitously expressed aggregation-prone expanded protein could also be a reflex of its subcellular localization

doi: 10.1093/brain/aww097 21

186 On the other hand, in a randomized controlled trial in 260 men with abnormal sperm number, motility, and morphology, 60 mg of saffron daily for 26 weeks resulted in no differences relative to placebo with regard to sperm density, motility, or morphology, or semen antioxidant capacity