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A single-cell transcriptomic study comparing primary bronchial epithelial cells obtained from donors with and without COPD found that exposure to menthol-flavored e-cigarette extract from 4 th -generation device caused hypoplasia of club cells and ciliated cells, and increased Notch signaling in both groups (112)

Vertical wrinkles form around your mouth

Patch's Maggie Fusek contributed to this report

As of September 2019, only Pennsylvania does not have laws regarding youth access to e-cigarettes

From stained teeth and gum disease to delayed healing and a higher risk of oral cancer, tobacco impacts every part of your smile