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found cells positive for the HCN type-4 channel, which is responsible for pacemaker activity, in biopsies of tissue from the PV-LA junction of AF patients (35)

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Usually, a quality cigar will evolve in flavour as it burns because the smoke and oil drawn through will influence the tobacco lower down

Supplementary MR methods supported this finding: MR-Egger (OR = 0.848), weighted median (OR = 0.441) and maximum likelihood (OR = 0.554) all showed OR 1, consistent in direction with the IVW estimate, further validating the observed positive causal relationship