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Synthesis of Results The primary meta-analysis pooled all RCTs across depression rating scales using standardized mean difference (SMD) random effects (REML)

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doi: 10.1038/s41419-022-05115-x 63 JiaoYYongCZhangRQiDWangD

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A glutamine residue replaces asparagine at position 8, a modification that may reduce spontaneous chemical rearrangements or hydrolysis of the peptide backbone