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The trend in the correction of mean serum sodium concentration over 48 h of treatment between the overall proactive and reactive groups and the high-risk ODS subgroup was shown in Fig

The induction of angiogenesis in the CNS has been reported to promote pathological conditions such as brain tumor growth, and sterile-venous malformations (SVM) (Vallon and Chang 2014)

However, concerns remain regarding the long-term efficacy of iPS cell-derived RPE therapies, particularly due to the risk of oncogenic mutations and tumorigenesis reported in both preclinical models and clinical observations 47,48

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