Abstract The study was based to find out the effect of iron deficiency anemia on glutathione concentration, and the level of peroxynitrite was taken as an indication of the change in oxidative stress levels for patients with iron deficiency anemia
[DOI] [PubMed] [Google Scholar] [26].Wilhelm D, Bender K, Knebeland AP
Indeed, intracerebroventricular infusion of PPA in rats decreases total glutathione in brain homogenates
doi: 10.3390/pharmaceutics13101542 142 ICfHoTRfPfH
Furthermore, leptin is also involved in the AMPK and cAMP-response element binding protein (CREB)-regulated transcription coactivator (CRTC) pathway ( In contrast to leptin, circulating APN concentrations are reduced in obese individuals, which is a phenomenon hypothesized to play a pivotal role in the pathogenesis of atherosclerosis and cardiovascular diseases associated with obesity and the metabolic syndrome ( In patients with PCOS, there is a significant increase in serum leptin and a corresponding decrease in APN levels (78, 80)
