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When experimenting with these methods, always emphasize safety first

"There has been an alarming rise in the use of e-cigarettes by teens, putting them at risk for lifelong addiction." The Institute of Medicine reports that 90% of daily smokers began using tobacco before turning 19

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Therefore, in order to detect a reduction in inhaled volume of 50 ml per cigarette (equivalent to one fewer cigarette per day for a 10-a-day smoker) with 80% power at an alpha level of 5%, we will recruit 128 participants

& Reaven, G