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For C max and AUC, geometric means and coefficients of variation were determined, and two-sided, paired t-tests with logarithmized values were performed

Researchers found some evidence that non-serious adverse effects were more common in people receiving nicotine e-cigarettes compared to behavioral support only or no support, and a low number of unwanted effects, including serious effects, were found in studies comparing nicotine e-cigarettes to nicotine replacement therapy