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First, an initial population was generated, then at each 1-year time step, the survivability of agents was evaluated based on mortality risk factors dependent on their tobacco use history (i.e., Mortality Sub-Model)

Mol Cell Biochem 279:105112 Nesnow S, Roop B, Lambert G et al (2002) DNA damage induced by methylated trivalent arsenicals is mediated by reactive oxygen species

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