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Obesity creates inflammatory environment and mechanical stress

For example, decreased sodium excretion (increasing levels) results in water retention and a condition known as volume overload, which causes swelling of tissues (edema)

Dietary Changes: Make necessary changes to your diet by including B12-rich foods like meat, eggs, dairy products and other sources of B12

Iron eux from astrocytes plays a role in remyelination

Overall, this work proposed a convenient, safe, and effective rectal drug delivery strategy, providing a new candidate for the prevention and treatment of radiation-induced proctitis, and also providing a reference for the design of multifunctional local delivery systems in radiation-associated tissue injury