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Methods Comprehensively search method of the literature by using Pubmed, ScienceDirect, ISI Web of Knowledge, and Google Scholar databases for articles published in peer-reviewed journals from mostly 2016 to 2021 and rare and older articles for the history part of tobacco were used

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(1998): Cannabinoid transmission and reward-related events

82 Ethical, Legal, and Health Issues with Illegal Performance-Enhancing Drugs Ethical, Legal, and Health Issues with Illegal Performance-Enhancing Drugs Epidemiology and Use Performance-Enhancing Drugs (PED) are pharmacological substances that are commonly used by competitive, professional, Olympic athletes, and non-athlete weightlifters to improve performance, muscle recovery, and prevent nutritional deficiencies