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The C677T polymorphism creates a restriction site for Hinf I, so the digestion of the polymerase chain reaction (PCR) products of the mutant allele generates two fragments (175 and 23 bp)

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TABLE 3 Degree of phase II conjugation of compounds detected in serum/plasma after intake of Pycnogenol and plasma protein binding of Pycnogenol constituents and metabolites

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