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These estimates were based on calculations assuming Hardy-Weinberg equilibrium and accurate AAT typing in these control populations, but it remains to be determined how significantly these estimates were affected by PI typing errors, new mutations, or migration from populations in Northern Europe

The manufactured products will be intended for both the domestic market and export

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According to the states behavior survey (Alaska Tobacco Facts, 2015), the majority of smokers (71%) want to quit

Preventing adolescents from smoking initiation is crucial in achieving this, as quitting smoking is challenging once habitualised and the probability of quitting is inversely proportional to initiation age (35, 36)