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Continued efforts resulted in an analog characterized by increased hydrophobicity, decreased hydrogen bonding potential coupled with increased metabolic stability bonding potential, and significantly increased metabolic stability [69,72]

For example, a systematic review of 17 studies examining BSO as a treatment for patients with diabetes and other metabolic conditions found significant improvements in fasting glucose, postmeal glucose, fasting insulin, hemoglobin A1c, and [Homeostatic Model Assessment for Insulin Resistance] (HOMA-IR)

Lister et al., 2008, 2009

Hussey, S

Concretely, astrocytes undergo polarization toward the neurotoxic A1 phenotype under SAH, which is mitigated by H4K8la