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Results Nicotine aerosol inhalation produces pharmacokinetics in pregnant rats resembling that of human cigarette smoking Nicotine aerosol in the breathing zone of the nose-only exposure chamber in our aerosol system has a droplet size distribution within the respirable diameter range 13,14 that results in deposition of nicotine in lung alveolar regions and rapid absorption into the pulmonary circulation, and then rapidly into the coronary and systemic circulations 11

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