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"I always tell my patients that if they have a bag of Doritos, they will eat it

However, data published in 2015 suggest that large numbers of youth are initiating e-cigarette use and that as many as half of these individuals do not smoke traditional combustible cigarettes. A recent report from the Centers for Disease Control and Prevention found that rates of e-cigarette use among high schoolers jumped from 4.5% in 2013 to 13.4% in 2014 tripling in just one year

This might lead to loss of power, thus compromising safety

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Other than for ethnicity ( 2 = 11.2, p = 0.025), there were no statistically significant differences in the characteristics of participants across the three experimental conditions