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The mechanisms of aging are the common root cause of these diseases, and healthy longevity and antiaging therapies can achieve broad-spectrum prevention or improvement of various diseases by intervening on the upstream mechanisms of aging hallmarks, thereby fundamentally improving the environment for disease occurrence

In various cancer models, PRODH has been described as a context-dependent tumor suppressor or promoter, depending on the metabolic state and microenvironment of the cell 63

Clinical trials have suggested that 3.6 g of curcumin taken orally for cancer treatment is a therapeutically effective dosage [146]

ROS, cell senescence, and novel molecular mechanisms in aging and age-related diseases

The US Anti-Doping Authority says there is a concerning lack of published clinical trial data because studies appear to have been cancelled or stopped without any published conclusions