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"The question was whether vape containing nicotine had negative effects on the ability to clear secretions from the airways similar to tobacco smoke," senior author Matthias Salathe, M.D., chair of internal medicine and a professor of pulmonary and critical care medicine at the University of Kansas Medical Center explained in a news release

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1 2 3 4 "Joe Camel: Post-mortem of a brand spokesperson"

Next, ARPE-19 cells were treated with Roxadustat, a specific PHD inhibitor, which stabilizes HIF-1 and HIF-2 in a concentration-dependent manner (Fig