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The hostility in your comment suggests that you are attaching this to a pre-existing narrative

Transgender youth use cigarettes at rates four times higher than cisgender youth and e-cigarettes at rates three times higher than cisgender youth, a 2019 study found

However, in patients with UC, restarting smoking after the cessation of smoking may worsen the severity and duration of UC, as observed and confirmed by clinicians treating patients with UC

If we consider pharmacodynamics, it is possible to speculate that combination therapy with different drugs having complementary modes of action should achieve better outcomes

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