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Sometimes agencies didnt even mind pursuing contradictory strategies: for instance, while touting the various health-promoting features of smoking (soothing the nerves, aiding digestion, providing a lift, etc.), cigarette advertisements also relied upon doctors testimonies to quell fears

One possible explanation for these regions of relative deactivation may be the shift from ventral to dorsal striatum that occurs as drug use becomes habitual and compulsive 29 , and the finding that dysfunctional inhibitory mechanisms in the prefrontal cortex also play a role in addictive behaviour 29, 30

The amount of dopamine released is not particularly high compared with other drugs, but nicotine also causes changes to the striatum

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