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Rheumatology (Oxford) 45 : 734740 Hyrich KL et al

Results: Neurological AHEs were the most frequently reported (n=418, 44.8%), followed by respiratory (n=336, 36.0%), nonspecific (n=196, 21.0%), digestive (n=93, 10.0%), and cardiovascular events (n=86, 9.2%)

In conjunction with the dark fruit, spices and tobacco notes, I feel transported to a British gentlemens club in Mayfair where High Tea has been served in one corner of a wood-paneled library and where members quietly smoke cheroots or pipes

The tobacco leaves are strung high up in barns and pine and herb fires are lit at the base

BMJ (Clinical Research ed) 309(6959):901911 ( Du K, Wei S, Wei Z, Frederick DT, Miao B, Moll T, Tian T, Sugarman E, Gabrilovich DI, Sullivan RJ, Liu L, Flaherty KT, Boland GM, Herlyn M, Zhang G (2021) Pathway signatures derived from on-treatment tumor specimens predict response to anti-PD1 blockade in metastatic melanoma