Montalban-Bravo G, Bose P, Alvarado Y, Daver NG, Ravandi F, Borthakur G, Takahashi K, Andreeff M , Cortes JE, DiNardo CD, Jabbor E, Kadia TM, Kornblau S, Ohanian M, Huang X, Nogueras-Gonzalez GM, Bodden K, Pierce S, Kantarjian HM, Garcia-Manero G
PMID: 41439202 Mol Cell Endocrinol2025 Dec 19:613:112721
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Because TB-500 is often overexpressed in malignant cells and facilitates angiogenesis, there is a theoretical risk that it could accelerate the growth of dormant tumors or increase metastatic capacity in certain cancer phenotypes