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It is not feasible to measure how smokers regulate their nicotine uptake in studies of disease risk, but the TTFC is a behavior that is strongly associated with the level of cotinine per cigarette smoked

The Secretary may make such a referral based on his own initiative, or upon the request of an interested person who demonstrates good cause

One of the most successful anti-smoking campaigns in history actually used the power of movies, and their idea of rebellion, to convince teenagers not to smoke: from 1998 to 2003, the provocative truth campaign in Florida teamed up with local government, advertising execs and actual teenagers to create TV spots

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So, in effect, we're fighting for