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Research demonstrates that Dihexa induces hippocampal spinogenesis with potency comparable to HGF itself, significantly increasing the number of dendritic spines per unit length of dendrite in both dissociated neuronal cultures and organotypic hippocampal slice preparations

The experimental greenhouse conditions were maintained at 30 C for the 14 h light period and 28 C for the 10 h dark period

In fact, reactive oxygen species (ROS) and peroxides (H2O2) upregulate the transsulfuration pathway (homocysteine towards cysteine and eventually the GSH-Px system) and downregulate the transmethylation (homocysteine towards methionine) (Figure 3)

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