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Johns wort Related articles: Curcumin Supplements: Decreasing Inflammation & Nootropics and Genetics: Smart Drugs and Your Genes Medications can also inhibit CYP1A2: Fluvoxamine is an SSRI that is a strong CYP1A2 inhibitor.[ref] Ciprofloxacin (antibiotic), methoxsalen, and oral contraceptives are considered moderate CYP1A2 inhibitors.[ref] If you take an inhibitor supplement along with drinking a caffeinated drink, you may find that the effects of caffeine last longer