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Tobacco Facts: How You Become Addicted to Cigarettes Tobacco facts show inhalation of nicotine via cigarette smoking produces the most rapid delivery of nicotine to the brain, with drug levels peaking within a few seconds of inhalation

A literature search was conducted using databases such as PubMed, Scopus, and Google Scholar, applying strict inclusion criteria: peer-reviewed studies published between 2010 and 2025 and keywords such as microplastics, smoking, tobacco, oxidative stress, pro-inflammatory cytokines, cell viability, regulatory policies, and health effects

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