These findings highlighted the importance of comprehensive policy measures, including regulatory enforcement, complemented by social and digital interventions aimed at reshaping peer norms and countering targeted advertising [44, 47, 48], especially to protect marginalized youth populations such as Orang Asli in Malaysia
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When there is an absence of evidence to provide confidence that there is benefit from implementing a new prevention service or when a conclusion of possible benefit requires a high level of speculation on linkages of uncertain evidence, but there is high certainty that some patients would be harmed or scarce health care resources expended, the task force may make a strong recommendation against service implementation
