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The consequent endothelial damage contributes to the formation and progression of atheromatous plaque, and reduces blood flow via thrombosis and vasospasm, thus causing cardiovascular disease

Based on machine-generated data comparing the levels of select harmful substances in Ploom aerosol relative to 1R6F reference cigarette smoke

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There are three likely contributing reasons for changing RRs over time: 1) the changing intensity of smoking over time, 2) decreasing mortality rates in never-smokers and 3) the time-lag from smoking to peak mortality harm

Which region has largest share of the tobacco market?Asia Pacific region has the largest share of the tobacco market