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They produce melanin and possess antioxidant defenses against ROS generated during melanogenesis

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Based on the mechanism of action of ganaxolone and work in preclinical animal models suggesting improved spatial memory function in an animal model of Angelman Syndrome (393), future investigation looking at the clinical value of this agent in anxiety disorders appears warranted

Neurological presentations of aceruloplasminemia include ataxia, involuntary movement, cognitive dysfunctions and parkinsonism