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Alternatively, CRISPR/Cas13 (e.g., CasRx or Cas13d) could be employed to specifically degrade YTHDF1 mRNA or even directly target SLC7A5 mRNA for degradation, offering more robust genetic evidence for the YTHDF1-SLC7A5 axis in PCOS-related ferroptosis

These included markers of oxidative stress (catalase, glutathione), indicators of long-term brain health (beta-amyloid) and neurotransmitters (acetylcholine, dopamine, GABA) in the brain.

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It may inhibit glucogenesis, lipid metabolism, adipocyte differentiation, and the transcriptional activities of several other nuclear receptors, including PPAR and ROR (Yin et al., 2007