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& O'Neill, L

Try to imagine the launch today of a highly addictive energy drink that smells at a distance, discolours your teeth and kills you in a protracted painful way a decade before you would have died otherwise 'But now with extra sexy!' It has been a hard-fought battle, but since the abolition of cigarette advertising on TV 60 years ago, more steps have been taken, smoking rates have dropped in the UK to around 10% and life expectancy has increased to 81 years

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Tobacco use also suppresses the expression of angiogenic markers such as vascular endothelial growth factor (VEGF), leading to decreased blood supply and impaired vascularization, which are crucial for bone healing