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It can be naturally derived from plants or manufactured synthetically in a lab
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Tobacco manufacturing remains geographically concentrated in historic growing and processing regions, with newer facilities also tied to logistics hubs and export channels
Eliminating combustionand consequently, dramatically reducing the levels of harmful chemicalsis the cornerstone of smoke-free product development
Harm-reduction experts have challenged those assertions, noting that a single year is far too short to assess the real consequences of prohibition, particularly given stockpiling, delayed behavioural change and the inevitable growth of illicit markets
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