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These factors suggest starting slightly higher than the minimum effective clinical dose to account for real-world variability

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Laboratory Tests During the initial treatment of patients with pernicious anemia, serum potassium must be observed closely the first 48 hours and potassium replaced if necessary

Side Effects: Cyanocobalamin is generally well-tolerated, but some patients might experience side effects, including

It remains undetermined whether or not the decreased Cyp7a1 expression in Insr P1195L/ +/HFD liver is the primary or a secondary change induced by HFD feeding plus insulin resistance