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S., Alothaid, H., Bantun, F., Alhazmi, A., Hakamy, A., Kaabi, Y

Cell-based Smad2/3 reporter assays using myoblast cell lines such as C2C12 transfected with a Smad-responsive luciferase construct are standard for quantifying trevogrumab's capacity to block myostatin-induced Smad2/3 transcriptional activation in a dose-dependent manner, typically expressed as an IC50 or neutralising dose

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