This dramatically helps to quantify the improvement during treatment, in this situation, twice-weekly intramuscular injections of hydroxocobalamin, and it also identified which symptoms probably were unrelated to the deficiency
Some people might also notice mild diarrhea or a feeling of swelling in their body, but these are typically temporary
Once anesthetized, the right knee joints of the animals were shaved, sterilized, and subjected to an intra-articular injection of collagenase type II
These can be given in the arm, leg, and shoulder amongst other places
NAD+s role in cellular repair has also made it a popular experimental therapy for improved health in aging, with the idea that maintaining higher NAD+ might support healthy aging processes