doi: 10.1016/s0361-3682(01)00052-6 45
reported no significant effect of PN L-carnitine supplementation on physical development indicators in their cohort of preterm infants (34)
This personalized and medically guided approach enhances safety, efficacy, and long-term healthspan benefits
For example, on average 63% of excess choline, and 31% of carnitine (+-13%) are converted to TMA [20] by an average gut profile - even if dysbiosis raised these values to 100%, it would still not meet the thresholds as above for precursor overload on a regular diet
A metabolite basis set was generated using MRSCloud(Hui et al., 2022), which included the following metabolites: ascorbate (Asc), aspartate (Asp), creatine (Cr), GABA, glycerophosphocholine (GPC), GSH, glutamine (Gln), Glu, myo-inositol (mI), lactate (Lac), N-acetyl aspartate (NAA), N-acetyl aspartyl glutamate (NAAG), phosphocholine (PCh), phosphorcreatine (PCr), phosphoryl ethanolamine (PE), scyllo-inositol (sI), and taurine (Tau)
