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Nicotine, a primary ingredient in tobacco, stimulates the release of dopamine in the brain, leading to feelings of pleasure and relief

Although there were no significant differences in monocytes and lymphocytes between smokers and non-smokers in the current and previous studies 52,55 , except for a reduction in the number of eosinophils, we observed a significant increase in TNF-, IL-2, IL-4, IL-6 and IL-10

The inflammation can cause persistent irritation in your nasal passages, leading to frequent sneezing along with other uncomfortable symptoms

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If the patient is not able to quit within the target date, it is possible to delay smoking suspension until the third or fourth week of treatment or when abstinence is reached [12]