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Collectively, these results suggest that PI3K/AKT signaling pathway activation may be involved in the pathogenesis of CS-induced pulmonary EMT and has potential therapeutic significance in COPD, lung cancer, and other smoking-related diseases

Background fluorescence was subtracted, and cholesterol content was calculated from a standard curve

Grant is, in fact, a reference to Richard Grant White (1822-1885), one of the most important American literary critics of his day (and the father of architect Stanford White)

Parker played a spirited sidekick in Footloose and a dance-crazed Army brat in Girls Just Want to Have Fun. Downey, Jr., joined S.N.L. for a year, in 1985, and landed his breakout role soon afterward, in the Bret Easton Ellis adaptation Less Than Zero. But he was struggling with substance abuse

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