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35 Regardless, the American Academy of Pediatrics recommends off-label NRT for youth who are moderately or severely addicted to nicotine because NRT is considered safer than continued cigarette and/or e-cigarette use

doi: 10.1371/journal.pbio.3001001

[28,29] The difference is usually small, 5 mg/dl or less, but this difference represents a 10% decrease and would be expected to affect atherogenesis to a significant degree