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[1] Many habitual users find themselves craving betel nuts throughout the day, especially during moments of fatigue or stress

Large numbers of people should be involved in the study

Previous studies showed that the expression of xCT gene and protein is decreased by chronic nicotine exposure (Hammad et al., 2021), which may be a homeostatic mechanism that compensates for exaggerated glutamate release in response to acute nicotine exposure

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