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We talk about tobacco as being sacred and being an important part of life, and being one of the first medicines out there, so you shouldn't disrespect it by smoking it recreationally, Makosky Daley says

Serum cotinine, a primary metabolite of nicotine, is directly proportional to the extent of tobacco smoke exposure and can serve as a reliable indicator of smoking intensity and tobacco smoke exposure 18,19

The animals were then exposed to an elevated T-maze and an open field

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If you want to dive into the details, you can learn more about the study on smoking cessation aids and see the full findings