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This is not to say that you cant do anything about it

A study in human embryonic stem cells also showed dysregulation of gene expression indicating a negative effect of e-cigarette use on heart development

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To be specific, there were 4 upregulated proteins (P01742, Q9BXG8, P06310, P19652) and 6 downregulated proteins (A0A0B4J1X8, Q9NZP8, P61604, Q01459, Q6UXB8, Q9Y5Y7) in patients with CS-induced OLK compared to healthy individuals (data unpublished), suggesting that the alteration of circulating exosomal proteins might play key roles in promoting OLK development and be considered as biomarkers for early diagnosis of OLK