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In general, tobacco-free nicotine products, like ZYN pouches or vapes, were originally developed as tools to help people quit smoking, and they are not intended for those who do not already use tobacco or nicotine products

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Additionally, females have a larger exposed area of mucosa (the vagina) in their genital region compared to men (the penile urethra)

Among non-smokers, exhaled carbon monoxide did not differ between the baseline, non-mask, and mask periods