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101 Interestingly, the deletion of the antioxidant gene transcription factor, nuclear erythroid 2 p45-related factor-2 (Nrf2), in DCs leads to oxidative stress in DCs and an enhanced responsiveness of DCs to airborne particulate matter that was characterized by a Th2-biased antigen-specific immune response

Ozone exposure irritates the respiratory system, causing coughing, throat irritation, chest tightness, and shortness of breath

Now, far fewer people smoke

Its good enough to loosen viscous saliva, mucus, and phlegm

As cigarette volumes decline due to anti-smoking initiatives and rising excise taxes, the shift toward non-combustible alternatives has gained traction