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Meltzer CC, Smith G, DeKosky ST, et al

PMID: 145 NeagEJSmithTJ

Once reconstituted, shelf life is 56 days when refrigerated

Given that fact that a significant percentage of the general population does not consume adequate dietary levels for several micronutrients (145), a daily multivitamin/mineral supplement could help improve micronutrient status and possibly have some cognitive and other health benefits

Topiramate blocks the ionotropic glutamate receptors in the trigeminothalamic pathway, as well as sodium and calcium channels with GABA signal enhancement (87)